Necrotizing Enterocolitis: A Narrative Review of Updated Therapeutic and Preventive Interventions

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Necrotizing Enterocolitis: A Narrative Review of Updated Therapeutic and Preventive Interventions

Context: Necrotizing enterocolitis (NEC) remains one of the most common causes of morbidity and mortality for premature infants in the neonatal intensive care unit (NICU). Many theories concerning its pathophysiology and inciting factors have been suggested but progression in preventing the onset of NEC has been minimal. While this article highlights the pathophysiology, management, outcomes of...

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Background: Necrotizing enterocolitis is one of the serious complications of prematurity. Eosinophilia has not been proposed as a classical laboratory abnormality in NEC. Previous studies suggest that eosinophilia during NEC may be a sign of allergic enterocolitis. Case presentation: We present a premature neonate with birth weight of 1280 grams with abdominal distention, bilious gastric resid...

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Necrotizing enterocolitis is a disease of unknown origin. Epidemiological observations emphasize the potential roles of  infection, enteric feeding and local vascular compromise of the Gastrointestinal tract in the pathogenesis of this disease. Clinical findings include signs of sepsis , plus abdominal distention , vomiting, bloody stool and occasionally , signs of intestinal perforation and pe...

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Necrotizing enterocolitis (NEC) is one of the most critical morbidities in preterm infants. The incidence of NEC is 7% in very-low-birth-weight infants, and its mortality is 15 to 30%. Infants who survive NEC have various complications, such as nosocomial infection, malnutrition, growth failure, bronchopulmonary dysplasia, retinopathy of prematurity, and neurodevelopmental delays. The most impo...

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ژورنال

عنوان ژورنال: Journal of Pediatrics Review

سال: 2016

ISSN: 2322-4401,2322-4398

DOI: 10.17795/jpr-6093